According to reports, a biotech company in the United States used 3D bioprinting technology to print out part of the liver. The results showed that the liver slices they produced were almost as functional as the human liver. The latest research is expected to accelerate the development of new drugs and bring hope to scientists who will eventually develop a complete and transplantable liver shop in the laboratory.
The liver is inherently regenerative, making it ideal for bioprinting. Bio-printing technology is a technology in which 3D printing technology prints live cells layer by layer under the precise guidance of a computer. The company hopes to improve the technology based on the printed liver and eventually create human organs in the laboratory.
In October, the company announced that they have created three-dimensional liver slices that can last up to 40 days to filter nutrients, toxins, and drugs. This is a major leap compared to the results of the April study. The liver slices produced by the company in April this year can only work for 5 days. The newly developed liver slices function almost as well as the human liver, reacting to antipyretic (an antipyretic analgesic that replaces aspirin) and other drugs.
However, the success of the latest research does not mean that doctors will soon be able to transplant organs printed by 3D printing technology into patients. Because complex organs like the liver, kidneys, and heart require a small network of blood vessels to stay healthy and contain other tiny structures, printing these tiny blood vessels and organs is a huge challenge for current 3D printing technologies.
The company's chief executive, Keith Murphy, said that despite this, the liver is still one of the easier-to-operate human organs because the liver is not as complex as the kidneys and other organs. Moreover, even small liver pieces that are only a few millimeters thick can help many patients.
The company plans to use its developed liver slices for drug testing, which will test the body's response to drugs, which will speed up the new drug research process and reduce its dependence on human testing. The company plans to release its 3D human liver product in 2014.
Another research project funded by the US Department of Defense plans to create a 2-foot-long "body chip" -- a tiny organ that is connected by an artificial blood vessel network. However, Murphy said that their liver products are likely to be listed first, and to humans, no matter how small 3D printing organs can benefit patients.
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