The spray dryer uses a nebulizer to disperse the liquid into fine droplets, and in the hot drying medium, the solvent is rapidly evaporated to form a dry powder. In general, spray drying is divided into four stages: liquid atomization; the mist group is mixed with the hot drying medium; the droplets are evaporated and dried; and the dried product is separated from the drying medium.
The author has learned that there are many common spray dryers, such as extract spray dryer, airflow spray dryer, centrifugal spray dryer, pressure spray dryer and so on. These common devices have their own characteristics and have contributed greatly to the production of the pharmaceutical industry.
Extract spray dryer
The extract spray dryer is a special form of centrifugal spray dryer. It is mainly composed of main engine, air filter, hot air distributor, liquid atomizer, powder collecting device and instrumentation control.
In the pre-treatment production process of traditional Chinese medicine preparations, most of the traditional Chinese medicine extracts are refined by complex processes such as water extraction and alcohol extraction, and some contain polysaccharides, animal oils and the like, high viscosity and high temperature. Deterioration and other components, in which the acidity and alkalinity, density, fluidity, annual and other properties of each batch of products are different due to the uncertainty of a large number of active ingredients, and abnormal phenomena will occur.
In order to prevent the material from sticking to the wall, the special spray dryer for traditional Chinese medicine extract is equipped with air sweeping wall and tower wall jacket cooling structure, which can effectively prevent the cohesive coking of the product and improve product quality and yield. The unique finished air delivery system can separate the dried finished product from the hot humid air in the system in time to avoid the possibility of moisture absorption and moisture agglomeration.
Airflow spray dryer
The airflow spray dryer mainly discharges air or water vapor from the nozzle through high speed, and separates the liquid into small droplets by friction, so that it completely contacts with the hot air to form heat exchange, and the whole process takes less than half a minute. It works well for viscous materials, which is unmatched by other spray dryers, and is also very convenient to operate.
Therefore, the airflow spray dryer has become an instant dryer in the industry, and is particularly suitable for use in solutions, emulsions, pastes, suspensions and even viscous materials. It is reported that the droplets are in full contact with hot air and exchange heat, and the entire drying process can be completed quickly within 10-30 seconds.
Centrifugal spray dryer
Centrifugal spray dryer is mainly used for spray drying of powder, granular solid products such as solution, emulsion, suspension, paste and traditional Chinese medicine extract, which has the advantages of high speed, high efficiency and few processes.
Air passes through the filter and heater into the air distributor at the top of the centrifugal spray dryer, and the hot air enters the dryer in a spiral shape. The liquid is pumped from the liquid tank through the filter to the centrifugal atomizer at the top of the dryer to spray the liquid into extremely small droplets.
The liquid and hot air are in parallel contact, the water evaporates quickly, and the product is dried in a very short time, and the finished product is discharged from the bottom of the drying tower and the cyclone, and the exhaust gas is discharged by the fan.
Pressure spray dryer
The pressure spray dryer is a device that can simultaneously complete drying and granulation. According to the process requirements, the pressure, flow rate and orifice size of the feed pump can be adjusted to obtain the desired spherical particles in a certain proportion.
The pressure spray dryer feeds the feed liquid (filtered feed liquid) into a pressure physicochemical device to atomize into small droplets through a high pressure of 2-20 MPa, and the droplets after the atomization (the surface area is greatly increased) are in full contact with the hot air. The drying process is quickly completed in 10-30 seconds, and the finished product of powder or fine particles is obtained by separation.
The working process of the equipment is that the liquid feeds through the high pressure input of the diaphragm pump, and sprays the mist droplets, and then flows down with the hot air. Most of the powder particles are collected by the bottom discharge port, and the exhaust gas and its fine powder are passed through the cyclone separator. Separation, the exhaust gas is discharged by the exhaust fan, the powder is collected by the pollination cylinder located at the lower end of the cyclone, and the secondary dust removal device can be equipped at the fan outlet, and the recovery rate is above 96-98%.
The author has learned that there are many common spray dryers, such as extract spray dryer, airflow spray dryer, centrifugal spray dryer, pressure spray dryer and so on. These common devices have their own characteristics and have contributed greatly to the production of the pharmaceutical industry.
Extract spray dryer
The extract spray dryer is a special form of centrifugal spray dryer. It is mainly composed of main engine, air filter, hot air distributor, liquid atomizer, powder collecting device and instrumentation control.
In the pre-treatment production process of traditional Chinese medicine preparations, most of the traditional Chinese medicine extracts are refined by complex processes such as water extraction and alcohol extraction, and some contain polysaccharides, animal oils and the like, high viscosity and high temperature. Deterioration and other components, in which the acidity and alkalinity, density, fluidity, annual and other properties of each batch of products are different due to the uncertainty of a large number of active ingredients, and abnormal phenomena will occur.
In order to prevent the material from sticking to the wall, the special spray dryer for traditional Chinese medicine extract is equipped with air sweeping wall and tower wall jacket cooling structure, which can effectively prevent the cohesive coking of the product and improve product quality and yield. The unique finished air delivery system can separate the dried finished product from the hot humid air in the system in time to avoid the possibility of moisture absorption and moisture agglomeration.
Airflow spray dryer
The airflow spray dryer mainly discharges air or water vapor from the nozzle through high speed, and separates the liquid into small droplets by friction, so that it completely contacts with the hot air to form heat exchange, and the whole process takes less than half a minute. It works well for viscous materials, which is unmatched by other spray dryers, and is also very convenient to operate.
Therefore, the airflow spray dryer has become an instant dryer in the industry, and is particularly suitable for use in solutions, emulsions, pastes, suspensions and even viscous materials. It is reported that the droplets are in full contact with hot air and exchange heat, and the entire drying process can be completed quickly within 10-30 seconds.
Centrifugal spray dryer
Centrifugal spray dryer is mainly used for spray drying of powder, granular solid products such as solution, emulsion, suspension, paste and traditional Chinese medicine extract, which has the advantages of high speed, high efficiency and few processes.
Air passes through the filter and heater into the air distributor at the top of the centrifugal spray dryer, and the hot air enters the dryer in a spiral shape. The liquid is pumped from the liquid tank through the filter to the centrifugal atomizer at the top of the dryer to spray the liquid into extremely small droplets.
The liquid and hot air are in parallel contact, the water evaporates quickly, and the product is dried in a very short time, and the finished product is discharged from the bottom of the drying tower and the cyclone, and the exhaust gas is discharged by the fan.
Pressure spray dryer
The pressure spray dryer is a device that can simultaneously complete drying and granulation. According to the process requirements, the pressure, flow rate and orifice size of the feed pump can be adjusted to obtain the desired spherical particles in a certain proportion.
The pressure spray dryer feeds the feed liquid (filtered feed liquid) into a pressure physicochemical device to atomize into small droplets through a high pressure of 2-20 MPa, and the droplets after the atomization (the surface area is greatly increased) are in full contact with the hot air. The drying process is quickly completed in 10-30 seconds, and the finished product of powder or fine particles is obtained by separation.
The working process of the equipment is that the liquid feeds through the high pressure input of the diaphragm pump, and sprays the mist droplets, and then flows down with the hot air. Most of the powder particles are collected by the bottom discharge port, and the exhaust gas and its fine powder are passed through the cyclone separator. Separation, the exhaust gas is discharged by the exhaust fan, the powder is collected by the pollination cylinder located at the lower end of the cyclone, and the secondary dust removal device can be equipped at the fan outlet, and the recovery rate is above 96-98%.
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